Cardiology

HAS-BLED

Estimates 1-year risk of major bleeding in patients with atrial fibrillation receiving oral anticoagulation. Modifiable factors should be addressed rather than withholding anticoagulation in moderate–high risk patients.

Creatinine > 2.26 mg/dL (200 µmol/L), chronic dialysis, or transplant

Cirrhosis, bilirubin > 2× ULN, or AST/ALT/ALP > 3× ULN

Prior major bleed, anaemia, or severe thrombocytopenia

Time in therapeutic range < 60% (warfarin only)

Antiplatelet agent or NSAID

Source

Pisters R, Lane DA, Nieuwlaat R, de Vos CB, Crijns HJGM, Lip GYH. A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest 2010.