Tropical

Scrub Typhus Severity

Counts validated severity predictors in confirmed or suspected scrub typhus infection. The presence of any organ failure raises mortality from < 5% to > 20%.

Respiratory failure (need for ventilatory support)

ARDS (PaO₂/FiO₂ < 200 with bilateral infiltrates)

Acute kidney injury (KDIGO ≥ 1)

Shock requiring vasopressors

Meningoencephalitis

Myocarditis

Severe hepatitis (transaminases > 10× ULN or jaundice)

Thrombocytopenia (< 50 ×10⁹/L)

Disseminated intravascular coagulation

Required ICU at admission

Source

Varghese GM, Trowbridge P, Janardhanan J, Thomas K, Peter JV, Mathews P, Abraham OC, Kavitha ML. Clinical profile and improving mortality trend of scrub typhus in South India. International Journal of Infectious Diseases 2014.

PMID 24661931 Ask House about this