Drug reference
agomelatine
Melatonin Receptor Agonist; Serotonin Receptor Antagonist · Antidepressant
Melatonin Receptor Agonist; Serotonin Receptor AntagonistAntidepressant
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Agomelatine is a melatonin receptor agonist and a 5HT2C receptor antagonist.
Indications
Treatment of depressionMay aid in ameliorating sleep disturbances often associated with depression
Related guidelines
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Textbook-sourced·Sources: Goodman & Gilman 14e·Updated: 2026-05-10