Abciximab
Severe
Database
Clinical effect not specified
Source: DDInter
Drug reference
anistreplase
Fibrinolytic drug · Fibrinolytic agent
Fibrinolytic drugFibrinolytic agent
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
- AbciximabSevereDatabaseDDInter
- AcalabrutinibSevereDatabaseDDInter
- ApixabanSevereDatabaseDDInter
- ArgatrobanSevereDatabaseDDInter
Mechanism
Anistreplase is generated by combining streptokinase with equimolar amounts of Lys-plasminogen. The active site is masked with an anisoyl group, which is slowly removed by deacylation after IV infusion. Like streptokinase, it does not distinguish between fibrin-bound and circulating plasminogen, producing a systemic lytic state.
Side effects
Common
Allergic reactionsHypotension
Drug interactions
Acalabrutinib
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Apixaban
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Argatroban
Severe
Database
Clinical effect not specified
Source: DDInter
Avapritinib
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Betrixaban
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Bivalirudin
Severe
Database
Clinical effect not specified
Source: DDInter
Cabozantinib
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Cangrelor
Severe
Database
Clinical effect not specified
Source: DDInter
Caplacizumab
Severe
Database
Clinical effect not specified
Source: DDInter
Dalteparin
Severe
Database
Clinical effect not specified
Source: DDInter
Dasatinib
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Ask House about anistreplase
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Sources: Harrison 22e·Verified: 2026-05-10 · House clinical team