Naltrexone
Severe
Database
Drug interaction classified as: absorption
Source: DDInter
Drug reference
bremelanotide
Melanocortin Receptor Agonist · Sexual Dysfunction Agent
Melanocortin Receptor AgonistSexual Dysfunction Agent
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
1 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactions
- NaltrexoneSevereDatabaseDDInter
Mechanism
Bremelanotide activates melanocortin receptors; the mechanism by which it improves sexual desire and related distress is unknown.
Indications
generalized hypoactive sexual desire disorder (HSDD) in premenopausal women
Dosing
- Adult
- self-administered injection 45 min prior to anticipated sexual activity
Contraindications
- women at high risk for cardiovascular disease
Side effects
Common
nauseaincreased blood pressure
Drug interactions
Related guidelines
Coronary angiography with renal dysfunction
CSI · Cardiology · 2020
Hypertensive disorders of pregnancy
FOGSI · Obstetrics & Gynaecology · 2019
Substance use disorders
NIMHANS · Psychiatry · 2022
Alcohol use disorder
MOHFW · Psychiatry · 2021
Generalised anxiety disorder and panic disorder
NICE · Psychiatry · 2020
Ask House about bremelanotide
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team