Ciprofloxacin
Moderate
Textbook-cited
Therapeutic failure of the antibiotic
Stagger administration by 2-3 hours
Source: KDT 7e · p949
Drug reference
calcium citrate
Calcium salt · Calcium supplement
Calcium saltCalcium supplement
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Provides elemental calcium for physiological functions. It is soluble in the presence of HCl.
Indications
Tetany (long-term oral therapy)Dietary supplement (growing children, pregnant, lactating and menopausal women)Osteoporosis (adjuvant role to alendronate/HRT/raloxifene)
Dosing
- Adult
- 1–1.5 g daily (oral, general calcium allowance); specific dietary allowances: Men 25–65 yr, women 25–50 yr and 51–65 yr if taking HRT: 1.0 g; Women 51–65 yr not taking HRT, every one > 65 yr: 1.5 g
- Pediatric
- Children 1–10 yr: 0.8–1.2 g; Young adult 11–24 yr: 1.2–1.5 g
Pharmacokinetics
Bioavailability
Absorption in patients taking PPIs/H2 blockers and elderly is satisfactory.
Side effects
Common
ConstipationBloatingExcess gas
Serious
- Myocardial infarction (27% higher incidence in subjects receiving calcium supplements)
Drug interactions
Doxycycline
Moderate
Textbook-cited
Therapeutic failure of the antibiotic
Stagger administration by 2-3 hours
Source: KDT 7e · p949
Levofloxacin
Moderate
Textbook-cited
Therapeutic failure of the antibiotic
Stagger administration by 2-3 hours
Source: KDT 7e · p949
Minocycline
Moderate
Textbook-cited
Therapeutic failure of the antibiotic
Stagger administration by 2-3 hours
Source: KDT 7e · p949
Moxifloxacin
Moderate
Textbook-cited
Therapeutic failure of the antibiotic
Stagger administration by 2-3 hours
Source: KDT 7e · p949
Norfloxacin
Moderate
Textbook-cited
Therapeutic failure of the antibiotic
Stagger administration by 2-3 hours
Source: KDT 7e · p949
Ofloxacin
Moderate
Textbook-cited
Therapeutic failure of the antibiotic
Stagger administration by 2-3 hours
Source: KDT 7e · p949
Tetracycline
Moderate
Textbook-cited
Therapeutic failure of the antibiotic
Stagger administration by 2-3 hours
Source: KDT 7e · p949
Related guidelines
Ask House about calcium citrate
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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team