Carboprost

Carboprost is a prostaglandin analogue that stimulates myometrial contractions. This action helps to reduce uterine bleeding, making it effective in treating postpartum haemorrhage caused by uterine atony, particularly when other oxytocic drugs are ineffective.

Adult

BY DEEP INTRAMUSCULAR INJECTION: 250 micrograms, repeated if necessary, at intervals of not less than 15 minutes.

Renal adjustment

Manufacturer advises avoid.

Hepatic adjustment

Manufacturer advises avoid in active hepatic disease.

Max dose

Total dose should not exceed 2 mg (8 doses)

• Cardiac disease
• pulmonary disease
• history of anaemia
• history of asthma
• history of diabetes
• history of epilepsy
• history of glaucoma
• history of hypertension
• history of hypotension
• history of jaundice
• history of raised intra-ocular pressure
• uterine scars
• untreated pelvic infection