Drug reference
cefuroxime axetil
Second generation cephalosporin · Antibiotic
Second generation cephalosporinAntibiotic
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
B
FDA category + note
Mechanism
Not yet extracted
Indications
Same as cefuroxime after hydrolysis in vivo
Pharmacokinetics
Bioavailability
oral effective, though absorption is incomplete
Metabolism
activity depends on in vivo hydrolysis and release of cefuroxime
Side effects
Common
Gastrointestinal side effects (e.g., diarrhea)
Serious
- Hypersensitivity reactions (rash to anaphylaxis)
- Serum sickness
- Stevens-Johnson syndrome
- Nephropathy
- Hematologic reactions (neutropenia, prolonged use)
- Neurotoxicity (seizure, high doses, renal impairment)
Pregnancy & lactation
Pregnancy
B
Drug interactions
1 additional unreviewed or low-confidence interaction hidden because their provenance or source detail is insufficient.
Related guidelines
Stroke and TIA — secondary prevention
AHA · Neurology · 2021
Acute dental pain and intraoral swelling
ADA_DENTAL · Dentistry · 2019
Infective endocarditis prevention
ADA_DENTAL · Dentistry · 2015
Community-acquired pneumonia
ICMR · Pulmonology · 2022
Extrapulmonary tuberculosis
ICMR · Infectious Diseases · 2022
Ask House about cefuroxime axetil
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Textbook-sourced·Sources: KD Tripathi 7e, Harrison 22e·Updated: 2026-05-10