Alfentanil
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
chlorzoxazone
Mephenesin congener · Skeletal muscle relaxant
Mephenesin congenerSkeletal muscle relaxant
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
- AlfentanilSevereDatabaseDDInter
- BenzhydrocodoneSevereDatabaseDDInter
- BuprenorphineSevereDatabaseDDInter
- ButorphanolSevereDatabaseDDInter
Mechanism
Not yet extracted
Indications
tension states associated with increased muscle tone
Pharmacokinetics
Duration
longer duration of action (than mephenesin)
Drug interactions
Benzhydrocodone
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Buprenorphine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Butorphanol
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Codeine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Dextropropoxyphene
Severe
Database
Drug interaction classified as: synergy, metabolism
Source: DDInter
Dezocine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Dihydrocodeine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Fentanyl
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Hydrocodone
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Hydromorphone
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Leflunomide
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Related guidelines
Other Mephenesin congener drugs
Ask House about chlorzoxazone
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team