Drug reference
ciraparantag
Synthetic small molecule · Antidote
Synthetic small moleculeAntidote
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Ciraparantag is a synthetic, small cationic molecule that is reported to bind dabigatran, rivaroxaban, apixaban, and edoxaban, as well as heparin and LMWH.
Indications
reversal of dabigatran, rivaroxaban, apixaban, edoxaban, heparin, and LMWH (currently in phase III clinical trials)
Related guidelines
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MOHFW · Endocrinology · 2021
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MOHFW · Infectious Diseases · 2012
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OTHER · Gastroenterology · 2015
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EASL · Gastroenterology · 2025
Trauma in elderly and frail patients
WSES · Surgery · 2023
Ask House about ciraparantag
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Textbook-sourced·Sources: Goodman & Gilman 14e·Updated: 2026-05-10