House
Sign inCreate account
Drug lookup
Drug reference

clobetasol butyrate

Moderately potent topical corticosteroid · Anti-inflammatory, Immunosuppressive, Antiproliferative

Moderately potent topical corticosteroidAnti-inflammatory, Immunosuppressive, Antiproliferative
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated

Mechanism

Benefits by virtue of antiinflammatory, immunosuppressive, vasoconstrictor and antiproliferative (for scaling lesions) actions.

Indications

Variety of dermatological conditions

Dosing

Adult
0.05% cream

Side effects

Common
Thinning of epidermisDermal atrophyTelangiectasiaStriaeEasy bruisingHypopigmentationDelayed wound healingFungal and bacterial infections
Serious
  • Adrenal pituitary suppression (with large, repeated amounts)
  • Cushing’s syndrome (rarely)

Related guidelines

Inflammatory bowel disease
OTHER · Gastroenterology · 2015
Gastric premalignant conditions
ACG · Gastroenterology · 2025
Preventive care in inflammatory bowel disease
ACG · Gastroenterology · 2025
Plaque psoriasis
IADVL · Dermatology · 2022
Acne vulgaris
IADVL · Dermatology · 2023

Other Moderately potent topical corticosteroid drugs

prednicarbate
0 brands

Ask House about clobetasol butyrate

Continue into a citation-backed clinical answer with the drug context already attached.

Open in workspaceAsk House about this drug

Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team