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clobetasol propionate

Potent topical corticosteroid · Anti-inflammatory, Immunosuppressive, Antiproliferative

Potent topical corticosteroidAnti-inflammatory, Immunosuppressive, Antiproliferative
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated

Mechanism

Benefits by virtue of antiinflammatory, immunosuppressive, vasoconstrictor and antiproliferative (for scaling lesions) actions.

Indications

Variety of dermatological conditionsSevere inflammatory conditionsUnresponsive eczemaPsoriasis

Dosing

Adult
0.05% cream

Side effects

Common
Thinning of epidermisDermal atrophyTelangiectasiaStriaeEasy bruisingHypopigmentationDelayed wound healingFungal and bacterial infections
Serious
  • Adrenal pituitary suppression (with large, repeated amounts)
  • Cushing’s syndrome (rarely)

Related guidelines

Plaque psoriasis
IADVL · Dermatology · 2022
Inflammatory bowel disease
OTHER · Gastroenterology · 2015
Gastric premalignant conditions
ACG · Gastroenterology · 2025
Preventive care in inflammatory bowel disease
ACG · Gastroenterology · 2025
Dengue fever
ICMR · Infectious Disease · 2022

Other Potent topical corticosteroid drugs

betamethasone benzoate
0 brands
betamethasone valerate
0 brands
dexamethasone sodium phosphate
0 brands
dexamethasone trimethyl-acetate
0 brands
halcinonide
0 brands

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Textbook-sourced·Sources: KD Tripathi 7e·Updated: 2026-05-10