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dalfopristin

Semisynthetic pristinamycin antibiotic · Antibacterial

Semisynthetic pristinamycin antibioticAntibacterial
CDSCO approved
EXCRETION
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
not curated
Top interactionssee all 12
  • AcalabrutinibSevereDatabaseDDInter
  • AlfentanilSevereDatabaseDDInter
  • AmiodaroneSevereDatabaseDDInter
  • AmitriptylineSevereDatabaseDDInter

Mechanism

Quinupristin/Dalfopristin is a combination of two semisynthetic pristinamycin antibiotics which together exert synergistic inhibition of bacterial protein synthesis.

Indications

serious nosocomial MRSA infectionsVRE infectionsother resistant gram-positive infections

Drug interactions

Acalabrutinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Alfentanil
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Amiodarone
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Amitriptyline
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Astemizole
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Avanafil
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Avapritinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Bepridil
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Bosutinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Brexpiprazole
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Brigatinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Butorphanol
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Related guidelines

Other Semisynthetic pristinamycin antibiotic drugs

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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team