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dehydroemetine

Alkaloid · Antiamoebic

AlkaloidAntiamoebic
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
X
FDA category + note

Mechanism

Equally effective as emetine.

Indications

Acute amoebic dysentery (used rarely for severe cases or when metronidazole produces severe allergic reaction/neurotoxicity)Amoebic liver abscess

Dosing

Adult
60–100 mg s.c./i.m. OD for not more than 10 days.

Side effects

Common
pain at injection sitedizzinessheadachegi symptoms
Serious
  • less cumulative than emetine
  • less toxic to the heart than emetine
  • cardiotoxicity

Pregnancy & lactation

Pregnancy

X

Related guidelines

Acute liver failure
ICMR · Gastroenterology · 2022
MASLD / non-alcoholic fatty liver disease
INASL · Hepatology · 2023
MASLD / non-alcoholic fatty liver disease
AASLD · Gastroenterology · 2023
Dengue fever
ICMR · Infectious Disease · 2022
Cirrhosis
OTHER · Hepatology · 2021

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Sources: KD Tripathi 7e, Harrison 22e·Verified: 2026-05-10 · House clinical team