Drug reference
deslorelin
GnRH agonist analogue · Palliative therapy of hormone-responsive tumors
GnRH agonist analoguePalliative therapy of hormone-responsive tumors
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
A synthetic agonist congener of GnRH. After a transient stimulation of gonadotropin secretion, it downregulates the GnRH receptor and inhibits gonadotropin secretion. Exhibits enhanced potency and prolonged duration of action compared to native GnRH.
Contraindications
- Pregnant women
Side effects
Common
Hot flashesDecreased bone densityVaginal dryness (women)Vaginal atrophy (women)Erectile dysfunction (men)
Related guidelines
Other GnRH agonist analogue drugs
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Textbook-sourced·Sources: Goodman & Gilman 14e·Updated: 2026-05-10