Aluminum Hydroxide
Severe
Database
Clinical effect not specified
Source: DDInter
Drug reference
doxercalciferol
Vitamin D analogue
Vitamin D analogue
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
10 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 10 →
- Aluminum HydroxideSevereDatabaseDDInter
- BurosumabSevereDatabaseDDInter
- CalcifediolSevereDatabaseDDInter
- CalcitriolSevereDatabaseDDInter
Mechanism
A prodrug (1α-hydroxyvitamin D2) that must first be activated by hepatic 25-hydroxylation.
Indications
secondary hyperparathyroidism in patients with chronic kidney disease (CKD)
Side effects
Serious
- hypercalcemia
- hypercalciuria
- hyperphosphatemia
Drug interactions
Burosumab
Severe
Database
Clinical effect not specified
Source: DDInter
Calcifediol
Severe
Database
Clinical effect not specified
Source: DDInter
Calcitriol
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Cholecalciferol
Severe
Database
Clinical effect not specified
Source: DDInter
Dihydrotachysterol
Severe
Database
Clinical effect not specified
Source: DDInter
Erdafitinib
Severe
Database
Clinical effect not specified
Source: DDInter
Ergocalciferol
Severe
Database
Clinical effect not specified
Source: DDInter
Paricalcitol
Severe
Database
Clinical effect not specified
Source: DDInter
Sucralfate
Severe
Database
Clinical effect not specified
Source: DDInter
2 additional low-confidence interactions hidden — those rows lack a documented mechanism or management plan in our sources.
Related guidelines
Chronic kidney disease — assessment and management
KDIGO · Nephrology · 2024
Chronic kidney disease — assessment and management
NICE · Nephrology · 2021
Chronic kidney disease — mineral and bone disorder
KDIGO · Nephrology · 2017
Diabetes management in chronic kidney disease
KDIGO · Nephrology · 2022
Hypertension in chronic kidney disease
KDIGO · Nephrology · 2021
Other Vitamin D analogue drugs
Ask House about doxercalciferol
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team