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Drug reference

enfortumab vedotin

antibody-drug conjugate (ADC), anti-Nectin4 · anticancer

antibody-drug conjugate (ADC), anti-Nectin4anticancer
CDSCO approved
EXCRETION
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
not curated
Top interactionssee all 12
  • AdalimumabSevereDatabaseDDInter
  • AmprenavirSevereDatabaseDDInter
  • AtazanavirSevereDatabaseDDInter
  • BaricitinibSevereDatabaseDDInter

Mechanism

Enfortumab vedotin is a Nectin4-directed antibody conjugated with the antimitotic MMAE.

Indications

locally advanced or metastatic urothelial cancer

Drug interactions

Adalimumab
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Amprenavir
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Atazanavir
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Baricitinib
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Boceprevir
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Ceritinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Certolizumab
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Cladribine
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Clarithromycin
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Clozapine
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Cobicistat
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Conivaptan
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Related guidelines

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Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team