Drug reference

iodoquinol

8-Hydroxyquinoline · Antiprotozoal (luminal amebicide)

8-HydroxyquinolineAntiprotozoal (luminal amebicide)

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

FDA category + note

Mechanism

Not yet extracted

Indications

Intestinal colonization with E. histolytica (as a luminal agent)Amebic colitis (in combination with metronidazole)Amebic liver abscess (in combination with metronidazole)

Pharmacokinetics

Bioavailability

poorly absorbed

Side effects

Common

headacherashpruritusthyrotoxicosisnauseavomitingabdominal paindiarrhea

Serious

Subacute myelo-optic neuropathy (especially with high doses/long periods)
Optic atrophy and permanent vision loss (in children with chronic diarrhea at high doses)
Peripheral neuropathy
optic neuritis
seizures
encephalopathy