Amiodarone
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
lisdexamfetamine
Prodrug (converted to D-amphetamine) · ADHD Agent
Prodrug (converted to D-amphetamine)ADHD AgentATC N06BA12
CDSCO approvedATC N06BA12
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
- AmiodaroneSevereDatabaseDDInter
- AmisulprideSevereDatabaseDDInter
- AnagrelideSevereDatabaseDDInter
- Arsenic TrioxideSevereDatabaseDDInter
Mechanism
Lisdexamfetamine is a therapeutically inactive prodrug that is converted primarily in the blood to lysine and D-amphetamine, the active component.
Indications
attention-deficit/hyperactivity disorder (ADHD)
Side effects
Common
decreased appetitedizzinessdry mouthfatigueheadacheinsomniairritabilitynasal congestionnasal pharyngitisupper respiratory infectionvomitingdecreased weight
Drug interactions
Amisulpride
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Anagrelide
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Arsenic Trioxide
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Bedaquiline
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Bepridil
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Bupropion
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Cabozantinib
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Ceritinib
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Chloroquine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Cisapride
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Citalopram
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Related guidelines
Hypertensive disorders of pregnancy
FOGSI · Obstetrics & Gynaecology · 2019
Substance use disorders
NIMHANS · Psychiatry · 2022
Alcohol use disorder
MOHFW · Psychiatry · 2021
Generalised anxiety disorder and panic disorder
NICE · Psychiatry · 2020
Chronic kidney disease — mineral and bone disorder
KDIGO · Nephrology · 2017
Ask House about lisdexamfetamine
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team