Adalimumab
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
mechlorethamine
nitrogen mustard, alkylating agent · anticancer, cytotoxic agent (topical for CTCL), vesicant (systemic toxicities noted for general class but not for mechlorethamine itself specifically with topical use, but strong vesicant properties described for the drug itself, p1348.) This is a bit ambiguous as to whether it applies to topical or systemic, but the text implies it's an inherent property of the drug class, and also specifically notes that
nitrogen mustard, alkylating agentanticancer, cytotoxic agent (topical for CTCL), vesicant (systemic toxicities noted for general class but not for mechlorethamine itself specifically with topical use, but strong vesicant properties described for the drug itself, p1348.) This is a bit ambiguous as to whether it applies to topical or systemic, but the text implies it's an inherent property of the drug class, and also specifically notes that
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
- AdalimumabSevereDatabaseDDInter
- BaricitinibSevereDatabaseDDInter
- CertolizumabSevereDatabaseDDInter
- CladribineSevereDatabaseDDInter
Mechanism
Not yet extracted
Indications
Hodgkin lymphomaNon-Hodgkin lymphoma
Side effects
Common
NauseaVomitingHaemodynamic changes
Serious
- Extravasation may cause sloughing
Drug interactions
Baricitinib
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Certolizumab
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Cladribine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Clozapine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Deferiprone
Severe
Database
Clinical effect not specified
Source: DDInter
Etanercept
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Fingolimod
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Golimumab
Severe
Database
Clinical effect not specified
Source: DDInter
Infliximab
Severe
Database
Clinical effect not specified
Source: DDInter
Leflunomide
Severe
Database
Clinical effect not specified
Source: DDInter
Measles Virus Vaccine Live Attenuated
Severe
Database
Clinical effect not specified
Source: DDInter
Related guidelines
Ask House about mechlorethamine
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: KD Tripathi 7e, Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team