Drug reference
mescaline
Psychedelic · Investigational (Antidepressant, Substance use disorder treatment, Migraine treatment, OCD treatment)
PsychedelicInvestigational (Antidepressant, Substance use disorder treatment, Migraine treatment, OCD treatment)
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Primary effects mediated by activation of 5HT2A receptors. Produces profound hallucinations.
Indications
Depression (in clinical trials)Substance use disorder (in clinical trials)Migraine (in clinical trials)Obsessive-compulsive disorder (in clinical trials)
Related guidelines
Other Psychedelic drugs
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Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team