Drug reference
metamizol
pyrazolone derivative · analgesic, antipyretic
pyrazolone derivativeanalgesic, antipyretic
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Metamizol is a potent and promptly acting analgesic and antipyretic. It is a poor antiinflammatory and not uricosuric.
Indications
analgesiaantipyresis
Dosing
- Adult
- 0.5–1.5 g oral/i.m./i.v.
Contraindications
- banned in USA and some European countries
- fixed dose combination with antispasmodics banned in India
Side effects
Common
gastric irritationpain at injection site
Serious
- agranulocytosis
- precipitous fall in BP (with i.v. injection)
Other pyrazolone derivative drugs
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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team