Drug lookup
Drug reference

mogamulizumab

humanized IgG1 antibody, anti-CCR4 · anticancer

humanized IgG1 antibody, anti-CCR4anticancer
CDSCO approved
EXCRETION
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
not curated
Top interactionssee all 12
  • AdalimumabSevereDatabaseDDInter
  • BaricitinibSevereDatabaseDDInter
  • CertolizumabSevereDatabaseDDInter
  • CladribineSevereDatabaseDDInter

Mechanism

Mogamulizumab is a humanized IgG1 antibody that targets CCR4, a G protein–coupled receptor that regulates trafficking of lymphocytes and is expressed in some T-cell malignancies.

Indications

relapsed or refractory mycosis fungoidesSézary disease (types of cutaneous T-cell lymphomas)

Side effects

Common
moderate to severe rashes
Serious
  • bone marrow suppression

Drug interactions

Adalimumab
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Baricitinib
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Certolizumab
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Cladribine
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Clozapine
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Deferiprone
Severe
Database

Clinical effect not specified

Source: DDInter

Etanercept
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Fingolimod
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Golimumab
Severe
Database

Clinical effect not specified

Source: DDInter

Infliximab
Severe
Database

Clinical effect not specified

Source: DDInter

Leflunomide
Severe
Database

Clinical effect not specified

Source: DDInter

Measles Virus Vaccine Live Attenuated
Severe
Database

Clinical effect not specified

Source: DDInter

Related guidelines

Ask House about mogamulizumab

Continue into a citation-backed clinical answer with the drug context already attached.

Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team