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nefopam

benzoxazocine derivative, nonopioid analgesic · analgesic

benzoxazocine derivative, nonopioid analgesicanalgesic
CDSCO approved
EXCRETION
not curated
INTERACTIONS
none in our sources
PREGNANCY
not curated

Mechanism

Nefopam is a nonopioid analgesic that does not inhibit prostaglandin synthesis.

Indications

traumatic painpostoperative painshort-lasting musculoskeletal painpain persistent and not adequately relieved by other analgesics

Dosing

Adult
30–60 mg TDS oral, 20 mg i.m. 6 hourly

Contraindications

  • epileptics

Side effects

Common
nausea (often dose limiting)
Serious
  • anticholinergic effects (dry mouth, urinary retention, blurred vision)
  • sympathomimetic effects (tachycardia, nervousness)

Related guidelines

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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team