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norgestrel

Synthetic Progestin (Gonane) · Contraceptive

Synthetic Progestin (Gonane)Contraceptive
CDSCO approved
EXCRETION
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
not curated
Top interactionssee all 12
  • AcitretinSevereDatabaseDDInter
  • AmprenavirSevereDatabaseDDInter
  • BexaroteneSevereDatabaseDDInter
  • BosentanSevereDatabaseDDInter

Mechanism

Not yet extracted

Indications

oral contraceptives

Pharmacokinetics

Half-life
16 h
Protein binding
to SHBG and albumin

Contraindications

  • undiagnosed vaginal bleeding
  • benign or malignant liver disease
  • known or suspected breast cancer

Side effects

Common
may decrease glucose tolerancemay increase LDL and reduce HDL

Drug interactions

Acitretin
Severe
Database

Clinical effect not specified

Source: DDInter

Amprenavir
Severe
Database

Drug interaction classified as: others

Source: DDInter

Bexarotene
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Bosentan
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Brigatinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Carbamazepine
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Carfilzomib
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Dabrafenib
Severe
Database

Clinical effect not specified

Source: DDInter

Encorafenib
Severe
Database

Clinical effect not specified

Source: DDInter

Eslicarbazepine
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Felbamate
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Fosamprenavir
Severe
Database

Clinical effect not specified

Source: DDInter

Related guidelines

Other Synthetic Progestin (Gonane) drugs

Ask House about norgestrel

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Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team