Drug reference

ospemifene

Selective Estrogen Receptor Modulator (SERM) · Gynecological Agent

Selective Estrogen Receptor Modulator (SERM)Gynecological Agent

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

6 major

SEVERE in our sources

PREGNANCY

—

not curated

Top interactionssee all 6 →

CarfilzomibSevereDatabaseDDInter
FluconazoleSevereDatabaseDDInter
LenalidomideSevereDatabaseDDInter
PomalidomideSevereDatabaseDDInter

Mechanism

Not yet extracted

Indications

vulvovaginal atrophydyspareunia

Side effects

Serious

increased risk of thromboembolism
potential thickening of endometrium

Drug interactions

Carfilzomib

Severe

Database

Drug interaction classified as: synergy

Source: DDInter

Fluconazole

Severe

Database

Drug interaction classified as: metabolism

Source: DDInter

Lenalidomide

Severe

Database

Clinical effect not specified

Source: DDInter

Pomalidomide

Severe

Database

Clinical effect not specified

Source: DDInter

Thalidomide

Severe

Database

Clinical effect not specified

Source: DDInter

Tranexamic Acid

Severe

Database

Clinical effect not specified

Source: DDInter

6 additional unreviewed or low-confidence interactions hidden because their provenance or source detail is insufficient.

Related guidelines

Preoperative cardiac evaluation for non-cardiac surgery

AHA · Cardiology · 2025

Acute diarrhoea in children

IAP · Pediatrics · 2022

Invasive candidiasis

IDSA · Infectious Diseases · 2016

Other Selective Estrogen Receptor Modulator (SERM) drugs

bazedoxifene

0 brands

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Textbook-sourced·Sources: Goodman & Gilman 14e·Updated: 2026-05-10