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rotavirus vaccine

live attenuated oral vaccine · vaccine

live attenuated oral vaccinevaccine
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
  • AbataceptSevereDatabaseDDInter
  • AbemaciclibSevereDatabaseDDInter
  • AcalabrutinibSevereDatabaseDDInter
  • AdalimumabSevereDatabaseDDInter

Mechanism

Rotavirus vaccines are live attenuated oral vaccines, based on human or human-bovine reassortant rotaviruses, designed to prevent severe dehydrating diarrhea in infants.

Indications

prevention of severe dehydrating diarrhea caused by rotavirus in infants

Dosing

Pediatric
RotaTeq is administered in a three-dose schedule, at 2, 4, and 6 months of age. Rotarix uses a two-dose schedule beginning at 2 months of age.

Side effects

Serious
  • An early live attenuated vaccine (Rotashield) was withdrawn after association with intussusception (a segmental telescoping collapse of the intestine). Rare rotavirus-associated intussusception risk with infection appears slightly higher at older ages with current vaccines.

Drug interactions

Abatacept
Severe
Database

Drug interaction classified as: others

Source: DDInter

Abemaciclib
Severe
Database

Drug interaction classified as: others

Source: DDInter

Acalabrutinib
Severe
Database

Drug interaction classified as: others

Source: DDInter

Adalimumab
Severe
Database

Drug interaction classified as: others

Source: DDInter

Aflibercept
Severe
Database

Drug interaction classified as: others

Source: DDInter

Aldesleukin
Severe
Database

Drug interaction classified as: others

Source: DDInter

Alefacept
Severe
Database

Drug interaction classified as: others

Source: DDInter

Alemtuzumab
Severe
Database

Drug interaction classified as: others

Source: DDInter

Altretamine
Severe
Database

Drug interaction classified as: others

Source: DDInter

Anakinra
Severe
Database

Drug interaction classified as: others

Source: DDInter

Antithymocyte Immunoglobulin (rabbit)
Severe
Database

Drug interaction classified as: others

Source: DDInter

Asparaginase Escherichia Coli
Severe
Database

Drug interaction classified as: others

Source: DDInter

Related guidelines

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Textbook-sourced·Sources: Goodman & Gilman 14e·Updated: 2026-05-10