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Drug reference

satralizumab

IL-6 receptor antibody · Immunosuppressant

IL-6 receptor antibodyImmunosuppressant
CDSCO approved
EXCRETION
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
not curated
Top interactionssee all 12
  • AbataceptSevereDatabaseDDInter
  • AdalimumabSevereDatabaseDDInter
  • AnakinraSevereDatabaseDDInter
  • BaricitinibSevereDatabaseDDInter

Mechanism

Antibody to IL-6R.

Indications

treatment of neuromyelitis optica spectrum disorder in adult patients who are positive for anti–aquaporin-4 antibody

Contraindications

  • live vaccines (avoid with il-6 blockade)

Side effects

Serious
  • increased risk of serious infections
  • serious cases of hepatoxicity

Drug interactions

Abatacept
Severe
Database

Clinical effect not specified

Source: DDInter

Adalimumab
Severe
Database

Drug interaction classified as: others

Source: DDInter

Anakinra
Severe
Database

Drug interaction classified as: others

Source: DDInter

Baricitinib
Severe
Database

Drug interaction classified as: others

Source: DDInter

Canakinumab
Severe
Database

Drug interaction classified as: others

Source: DDInter

Certolizumab
Severe
Database

Drug interaction classified as: others

Source: DDInter

Cladribine
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Clozapine
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Deferiprone
Severe
Database

Clinical effect not specified

Source: DDInter

Etanercept
Severe
Database

Drug interaction classified as: others

Source: DDInter

Fingolimod
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Golimumab
Severe
Database

Clinical effect not specified

Source: DDInter

Related guidelines

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Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team