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sincalide

CCK peptide analogue · Diagnostic agent

CCK peptide analogueDiagnostic agentATC V04CW02
CDSCO approvedATC V04CW02
EXCRETION
not curated
INTERACTIONS
none in our sources
PREGNANCY
not curated

Mechanism

Sincalide is the C-terminal octapeptide of cholecystokinin (CCK). CCK is a hormone that delays gastric emptying, causes gallbladder contraction, stimulates pancreatic enzyme secretion, increases intestinal motility, and promotes satiety.

Indications

Stimulating gallbladder contraction (diagnostic testing)Stimulating pancreatic secretion (diagnostic testing)Accelerating barium transit through the small bowel (diagnostic testing)

Pharmacokinetics

Onset
5 to 15 min

Side effects

Common
NauseaVomitingDiarrheaSweatingLight-headednessHeadacheAllergic reactions

Related guidelines

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Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team