Drug reference
sodium alginate
Anti-reflux agent · Antacid (adjuvant)
Anti-reflux agentAntacid (adjuvant)
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Sodium alginate forms a thick frothy layer that floats on the gastric contents like a raft, preventing contact of acid with the esophageal mucosa. It does not affect lower esophageal sphincter tone.
Indications
Gastroesophageal reflux disease (GERD) (in combination with antacids)
Related guidelines
Gastro-oesophageal reflux disease
ISG · Gastroenterology · 2022
Coeliac disease
OTHER · Gastroenterology · 2016
Inflammatory bowel disease
OTHER · Gastroenterology · 2015
Preventive care in inflammatory bowel disease
ACG · Gastroenterology · 2025
Chronic kidney disease — assessment and management
KDIGO · Nephrology · 2024
Ask House about sodium alginate
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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team