Drug reference
trioxsalen
Melanizing agent, Synthetic psoralen, Furocoumarin · Melanizing agent
Melanizing agent, Synthetic psoralen, FurocoumarinMelanizing agent
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Sensitizes skin to sunlight, which then induces erythema, inflammation, and pigmentation. On photoactivation, it stimulates melanocytes and induces their proliferation.
Indications
VitiligoAcceleration of tanningLichen planusUrticaria pigmentosaAtopic dermatitisCutaneous T cell lymphoma
Dosing
- Adult
- Oral: 5 mg, 25 mg tablets; Topical: 0.2% lotion
Side effects
Common
MottlingErythemaBurnsBlisteringPremature ageing of skinGastric discomfortNervousnessInsomnia
Related guidelines
Other Melanizing agent, Synthetic psoralen, Furocoumarin drugs
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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team