Drug reference

ulipristal

Selective progesterone receptor modulator (SPRM) · Emergency Contraceptive

Selective progesterone receptor modulator (SPRM)Emergency Contraceptive

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

FDA category + note

Mechanism

It inhibits ovulation by suppressing LH surge as well as by direct effect on follicular rupture. In addition, its action on endometrium can interfere with implantation.

Indications

Emergency contraceptive

Dosing

Adult: 30 mg single dose as soon as possible, but within 120 hours of intercourse

Side effects

Common

HeadacheNauseaVomitingAbdominal painMenstrual delayOvarian cysts (few cases)

Pregnancy & lactation

Pregnancy

Related guidelines

Snakebite envenomation

MOHFW · Emergency Medicine · 2021

Preoperative cardiac evaluation for non-cardiac surgery

AHA · Cardiology · 2025

Acute diarrhoea in children

IAP · Pediatrics · 2022

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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team