Drug reference
vaccinia virus vaccine
live attenuated Orthopoxvirus vaccine · vaccine
live attenuated Orthopoxvirus vaccinevaccine
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Vaccinia virus vaccine is a live attenuated Orthopoxvirus vaccine, developed through multiple passages in cell culture to reduce virulence while retaining immunogenicity, providing protection against smallpox.
Indications
prevention of smallpoxnon-emergency use for laboratory and healthcare workers exposed occupationally to vaccinia virus, recombinant vaccinia viruses, or other orthopoxviruses (monkeypox, cowpox virus)
Related guidelines
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Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team