Cladribine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
valrubicin
Anthracycline analogue · Antineoplastic
Anthracycline analogueAntineoplastic
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
2 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactions
- CladribineSevereDatabaseDDInter
- HexaminolevulinateSevereDatabaseDDInter
Mechanism
Valrubicin is a semisynthetic analogue of doxorubicin with antineoplastic activity via mechanisms similar to other anthracyclines.
Indications
Intravesicular treatment of bladder cancer
Dosing
- Adult
- Once a week for 6 weeks, 800 mg are instilled into the bladder.
Pharmacokinetics
Bioavailability
Less than 10% of instilled drug is absorbed systemically.
Side effects
Common
Bladder irritation
Drug interactions
Hexaminolevulinate
Severe
Database
Clinical effect not specified
Source: DDInter
3 additional low-confidence interactions hidden — those rows lack a documented mechanism or management plan in our sources.
Related guidelines
Ask House about valrubicin
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Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team