Adalimumab
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Drug reference
Abatacept
Immunosuppressant · Antirheumatic
ImmunosuppressantAntirheumatic
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
- AdalimumabSevereDatabaseDDInter
- BaricitinibSevereDatabaseDDInter
- CertolizumabSevereDatabaseDDInter
- CladribineSevereDatabaseDDInter
Mechanism
Abatacept prevents the full activation of T-lymphocytes.
Indications
Moderate to severe active rheumatoid arthritis (in combination with methotrexate, in patients unresponsive to other DMARDs, including methotrexate or a tumour necrosis factor (TNF) inhibitor)Granulomatosis with polyangiitis (implied use for patient alert card)Microscopic polyangiitis (implied use for patient alert card)Pemphigus vulgaris (implied use for patient alert card)prophylaxis of organ transplant rejectionautoimmunity trialsrheumatoid arthritis in patients resistant to other drugs
Dosing
- Adult
- maximum cumulative cyclophosphamide dose, or . cyclophosphamide is contra-indicated or not tolerated, or . the patient has not completed their family, and treatment with cyclophosphamide may materially affect their fertility, or . the disease has remained active or progressed despite a course of cyclophosphamide lasting 3–6 months or . the patient has had uroepithelial malignancy.…
Contraindications
- Not recommended for use in combination with TNF inhibitors
Drug interactions
Baricitinib
Severe
Database
Drug interaction classified as: others
Source: DDInter
Certolizumab
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Cladribine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Etanercept
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Fingolimod
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Golimumab
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Infliximab
Severe
Database
Drug interaction classified as: synergy.
Source: DDInter
Leflunomide
Severe
Database
Drug interaction classified as: others.
Source: DDInter
Measles Virus Vaccine Live Attenuated
Severe
Database
Drug interaction classified as: others
Source: DDInter
Mumps Virus Strain B Level Jeryl Lynn Live Antigen
Severe
Database
Clinical effect not specified
Source: DDInter
Natalizumab
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Related guidelines
Other Immunosuppressant drugs
Ask House about Abatacept
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Sources: Goodman & Gilman 14e, BNF·Verified: 2026-05-13 · House clinical team