Drug reference
ceftizoxime
β-Lactam antibiotic · Antibacterial
β-Lactam antibioticAntibacterialATC null
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
X
FDA category + note
Mechanism
null
Indications
Prophylaxis for dirty/contaminated surgical woundsSimilar to cefotaximeInhibits B. fragilis
Dosing
- Adult
- 1 g i.v. 12 hourly for 5 days (dirty contaminated wounds)
Pharmacokinetics
Half-life
1.5–2 hr
Metabolism
not metabolized
Excretion
by the kidney at a slower rate
Pregnancy & lactation
Pregnancy
X
Related guidelines
Venous thromboembolism prophylaxis
ASH · Haematology · 2018
Infective endocarditis prevention
ADA_DENTAL · Dentistry · 2015
Infective endocarditis prevention
NICE · Cardiology / Dentistry · 2008
Infective endocarditis prevention
AHA · Cardiology / Dentistry · 2007
Acute dental pain and intraoral swelling
ADA_DENTAL · Dentistry · 2019
Other β-Lactam antibiotic drugs
Ask House about ceftizoxime
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team