House
Sign inCreate account
Drug lookup
Drug reference

cenobamate

Sodium Channel Modulator, GABAA receptor allosteric modulator · Antiepileptic, Antiseizure Agent

Sodium Channel Modulator, GABAA receptor allosteric modulatorAntiepileptic, Antiseizure Agent
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
  • AvapritinibSevereDatabaseDDInter
  • AxitinibSevereDatabaseDDInter
  • BedaquilineSevereDatabaseDDInter
  • BenzhydrocodoneSevereDatabaseDDInter

Mechanism

Not yet extracted

Drug interactions

Avapritinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Axitinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Bedaquiline
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Benzhydrocodone
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Bosutinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Brigatinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Buprenorphine
Severe
Database

Drug interaction classified as: synergy

Source: DDInter

Butorphanol
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Capmatinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Citalopram
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Cobimetinib
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Daclatasvir
Severe
Database

Drug interaction classified as: metabolism

Source: DDInter

Related guidelines

Initial monotherapy for newly diagnosed epilepsy
ILAE · Neurology · 2013
Status epilepticus
AAN · Neurology · 2020
Functional (psychogenic non-epileptic) seizures
AAN · Neurology · 2026
Initial monotherapy for newly diagnosed epilepsy
IAN · Neurology · 2023

Ask House about cenobamate

Continue into a citation-backed clinical answer with the drug context already attached.

Open in workspaceAsk House about this drug

Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team