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Drug reference

daridorexant

Orexin receptor antagonist

Orexin receptor antagonist
CDSCO approved
EXCRETION
not curated
INTERACTIONS
none in our sources
PREGNANCY
not curated

Mechanism

Blocks the wake-promoting effects of the orexin neuropeptides.

Indications

Insomnia

Side effects

Common
Morning sedation
Serious
  • Hypnagogic hallucinations
  • Sleep paralysis

Other Unclassified drugs

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Sources: Harrison 22e·Verified: 2026-05-10 · House clinical team