Alfentanil
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Drug reference
dexfenfluramine
Appetite suppressant (withdrawn from market)
Appetite suppressant (withdrawn from market)
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactionssee all 12 →
- AlfentanilSevereDatabaseDDInter
- AlmotriptanSevereDatabaseDDInter
- AmitriptylineSevereDatabaseDDInter
- AmoxapineSevereDatabaseDDInter
Mechanism
Promotes the release of 5HT and blocks its reuptake.
Side effects
Serious
- Life-threatening heart valve disease
- Pulmonary hypertension
- Echocardiographic abnormalities
- Valvular defects
- Sudden deaths
Drug interactions
Almotriptan
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Amitriptyline
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Amoxapine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Amphetamine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Benzphetamine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Bupropion
Severe
Database
Drug interaction classified as: metabolism
Source: DDInter
Buspirone
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Citalopram
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Clomipramine
Severe
Database
Drug interaction classified as: synergy
Source: DDInter
Cyclobenzaprine
Severe
Database
Clinical effect not specified
Source: DDInter
Desipramine
Severe
Database
Clinical effect not specified
Source: DDInter
Other Unclassified drugs
Ask House about dexfenfluramine
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Sources: KD Tripathi 7e, Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team