Drug reference

Dicycloverine hydrochloride

Antimuscarinic · Gastrointestinal Antispasmodic

Also known as Dicyclomine hydrochloride

AntimuscarinicGastrointestinal Antispasmodic

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

Not known to be harmful; manufacturer advises use only if essential.

FDA category + note

Mechanism

Dicycloverine hydrochloride exerts an antimuscarinic action, which is less marked than atropine sulfate. It may also possess a direct action on smooth muscle. These actions collectively lead to reduced intestinal motility.

Indications

Symptomatic relief of gastro-intestinal disorders characterised by smooth muscle spasmIrritable bowel syndrome

Dosing

Adult: 10–20 mg 3 times a day
Pediatric: Child 6–23 months: 5–10 mg 3–4 times a day, dose to be taken 15 minutes before feeds; Child 2–11 years: 10 mg 3 times a day; Child 12–17 years: 10–20 mg 3 times a day
Max dose: 60 mg daily