Influenza Virus Vaccine
Moderate
Textbook
Small increase in febrile seizures.
The increase of febrile seizures when combining these vaccines is small, and the CDC does not recommend delivering them on separate days.
Source: G&G 14e · p812
Drug reference
diphtheria toxoid
bacterial toxoid vaccine · vaccine
bacterial toxoid vaccinevaccine
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Diphtheria toxoid is produced by deactivating the toxin isolated from Corynebacterium diphtheriae using formaldehyde or through genetic modification (e.g., CRM197). The native toxin's A subunit ADP-ribosylates eukaryotic elongation factor 2 (eEF-2), thereby inhibiting protein translation.
Indications
prevention of diphtheria
Dosing
- Pediatric
- immunize infants beginning at about 2 months, typically as part of the combination DTaP vaccine
Drug interactions
Related guidelines
Other bacterial toxoid vaccine drugs
Ask House about diphtheria toxoid
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team