Influenza Virus Vaccine
Moderate
Textbook
Small increase in febrile seizures.
The increase of febrile seizures when combining these vaccines is small, and the CDC does not recommend delivering them on separate days.
Source: G&G 14e · p812
Drug reference
tetanus toxoid
bacterial toxoid vaccine · vaccine
bacterial toxoid vaccinevaccine
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Tetanus toxoid induces an immune response against the tetanus toxin secreted by Clostridium tetani. The native toxin causes prolonged spasms and tetany by cleaving synaptobrevin and inhibiting neurotransmitter exocytosis in the nervous system.
Indications
prevention of tetanus
Dosing
- Adult
- Tdap and Td are booster immunizations that offer continued protection from tetanus for adolescents and adults. Td or Tdap booster every 10 years.
- Pediatric
- immunization usually begins at about age 2 months, as a component of the combination DTaP vaccine
Drug interactions
Related guidelines
Other bacterial toxoid vaccine drugs
Ask House about tetanus toxoid
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team