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Drug reference

emetine

Drug monograph

CDSCO approved
EXCRETION
not curated
INTERACTIONS
none in our sources
PREGNANCY
X
FDA category + note

Mechanism

Not yet extracted

Indications

Acute amoebic dysentery (rapid symptomatic relief, but not curative alone)Amoebic liver abscessLiver fluke infestation

Dosing

Adult
Not to be repeated within 6 weeks

Pharmacokinetics

Bioavailability
Cannot be given orally (vomited out).
Excretion
Administered by s.c. or i.m. injection.

Side effects

Common
toxicity on heart and skeletal musclenauseavomiting (due to CTZ stimulation and gastric irritation)abdominal crampsdiarrhoeaweaknessstiffness of musclesmyositishypotensionECG changespain at injection sitedizzinessheadachegi symptoms
Serious
  • myocarditis (high systemic toxicity)
  • cumulative toxicity (if used for more than 10 days)
  • cardiotoxicity

Pregnancy & lactation

Pregnancy

X

Related guidelines

Other Unclassified drugs

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Sources: KD Tripathi 7e, Harrison 22e·Verified: 2026-05-10 · House clinical team