Berotralstat
Severe
Database
Drug interaction classified as: absorption
Source: DDInter
Drug reference
enasidenib
IDH2 inhibitor · Antineoplastic agent
IDH2 inhibitorAntineoplastic agent
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
2 major
SEVERE in our sources
PREGNANCY
D
FDA category + note
Top interactions
- BerotralstatSevereDatabaseDDInter
- RosuvastatinSevereDatabaseDDInter
Mechanism
Enasidenib is an orally bioavailable IDH2 inhibitor.
Indications
relapsed or refractory AML with an IDH2 mutation
Side effects
Serious
- differentiation syndrome (can be fatal)
Pregnancy & lactation
Pregnancy
D
Drug interactions
Rosuvastatin
Severe
Database
Clinical effect not specified
Source: DDInter
10 additional low-confidence interactions hidden — those rows lack a documented mechanism or management plan in our sources.
Related guidelines
Ask House about enasidenib
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: Goodman & Gilman 14e, Harrison 22e·Verified: 2026-05-10 · House clinical team