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gallium nitrate

Bone resorption inhibitor · Hypercalcaemia treatment

Bone resorption inhibitorHypercalcaemia treatment
CDSCO approved
EXCRETION
not curated
INTERACTIONS
12 major
SEVERE in our sources
PREGNANCY
not curated
Top interactionssee all 12
  • AmikacinSevereDatabaseDDInter
  • Amphotericin BSevereDatabaseDDInter
  • CidofovirSevereDatabaseDDInter
  • DeferasiroxSevereDatabaseDDInter

Mechanism

A potent inhibitor of bone resorption, acting by depressing the ATP-dependent proton pump at the ruffled membrane of osteoclasts.

Indications

Resistant cases of hypercalcaemia

Dosing

Adult
Continuous i.v. infusion daily for 5 days.

Side effects

Serious
  • Nephrotoxicity

Drug interactions

Amikacin
Severe
Database

Clinical effect not specified

Source: DDInter

Amphotericin B
Severe
Database

Drug interaction classified as: others

Source: DDInter

Cidofovir
Severe
Database

Clinical effect not specified

Source: DDInter

Deferasirox
Severe
Database

Clinical effect not specified

Source: DDInter

Diatrizoate
Severe
Database

Clinical effect not specified

Source: DDInter

Everolimus
Severe
Database

Clinical effect not specified

Source: DDInter

Gentamicin
Severe
Database

Clinical effect not specified

Source: DDInter

Human Cytomegalovirus Immune Globulin
Severe
Database

Clinical effect not specified

Source: DDInter

Inotersen
Severe
Database

Clinical effect not specified

Source: DDInter

Iodipamide
Severe
Database

Clinical effect not specified

Source: DDInter

Iodixanol
Severe
Database

Clinical effect not specified

Source: DDInter

Iohexol
Severe
Database

Clinical effect not specified

Source: DDInter

Related guidelines

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Sources: KD Tripathi 7e·Verified: 2026-05-10 · House clinical team