Drug reference
gefapixant
Drug monograph
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
—
not curated
Mechanism
Gefapixant is a P2X3 receptor antagonist. It inhibits ATP binding to P2X3 receptors, thereby reducing the stimulation that leads to coughing.
Indications
refractory cough
Related guidelines
Other Unclassified drugs
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Sources: Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team