Drug reference

gm-csf

Colony-stimulating factor (CSF). Augments bone marrow production of PMNs.

CDSCO approved

EXCRETION

—

not curated

INTERACTIONS

—

none in our sources

PREGNANCY

—

not curated

Mechanism

Not yet extracted

Indications

Primary prophylaxis of febrile neutropenia (if probability is ≥20%)Primary prophylaxis of febrile neutropenia (if patient has preexisting neutropenia or active infection)Primary prophylaxis of febrile neutropenia (if age >65 years treated for lymphoma with curative intent or other tumors by similar regimens)Primary prophylaxis of febrile neutropenia (if poor performance status)Primary prophylaxis of febrile neutropenia (if extensive prior chemotherapy)Primary prophylaxis of febrile neutropenia (dose-dense regimens in a clinical trial or with strong evidence of benefit)Secondary prophylaxis of febrile neutropenia (if febrile neutropenia occurred in previous cycle)Secondary prophylaxis of febrile neutropenia (if prolonged neutropenia even without fever delays therapy)Mobilize stem cells from marrow in bone marrow or peripheral blood stem cell transplantationHasten myeloid recovery in bone marrow or peripheral blood stem cell transplantation