Drug reference directory
Drug reference

Histamine

Vitamin · Unknown

VitaminUnknown
CDSCO approvedSchedule H
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
, in breastfeeding women, and in children under 12 years. All
FDA category + note

Mechanism

Histamine is an endogenous mediator primarily involved in immediate, rapidly-evolving reactions compatible with an immunological mechanism, such as drug allergy. Its release can lead to clinical features like anaphylaxis, with erythema, urticaria or angioedema, hypotension, and bronchospasm.

Pharmacokinetics

Metabolism
Histamine undergoes methylation.

Pregnancy & lactation

Pregnancy

, in breastfeeding women, and in children under 12 years. All

Drug interactions

Adrenaline
Moderate
Textbook

Physiological antagonism on bronchial muscles and blood pressure.

Source: KDT 7e · p58

11 additional unreviewed or low-confidence interactions hidden because their provenance or source detail is insufficient.

Related guidelines

Other Vitamin drugs

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Textbook-sourced·Sources: KD Tripathi 7e, Katzung, BNF, Nelson·Updated: 2026-05-10