Potassium Chloride
Severe
Database
Clinical effect not specified
Source: DDInter
Drug reference
homatropine
Semisynthetic derivative, muscarinic antagonist · Anticholinergic
Semisynthetic derivative, muscarinic antagonistAnticholinergic
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
4 major
SEVERE in our sources
PREGNANCY
—
not curated
Top interactions
- Potassium ChlorideSevereDatabaseDDInter
- Potassium CitrateSevereDatabaseDDInter
- TopiramateSevereDatabaseDDInter
- ZonisamideSevereDatabaseDDInter
Mechanism
Not yet extracted
Indications
Ophthalmological examination (cycloplegia and mydriasis induction)Irritable bowel syndrome (as methylbromide derivative, formerly)Peptic ulcer disease (as methylbromide derivative, formerly)Antitussive combination with hydrocodone (as methylbromide derivative)cycloplegiamydriasisiritisuveitisMydriasis and cycloplegia for refraction testing
Pharmacokinetics
Onset
acts in 45–60 min
Duration
Shorter duration of action than atropine
Side effects
Common
Unsatisfactory cycloplegia in children (who have high ciliary muscle tone)
Drug interactions
Potassium Citrate
Severe
Database
Clinical effect not specified
Source: DDInter
Topiramate
Severe
Database
Clinical effect not specified
Source: DDInter
Zonisamide
Severe
Database
Clinical effect not specified
Source: DDInter
8 additional low-confidence interactions hidden — those rows lack a documented mechanism or management plan in our sources.
Related guidelines
Irritable bowel syndrome
ISG · Gastroenterology · 2023
Inflammatory bowel disease
OTHER · Gastroenterology · 2015
Preventive care in inflammatory bowel disease
ACG · Gastroenterology · 2025
Acute coronary syndrome in chronic kidney disease
CSI · Cardiology · 2020
Empirical antimicrobial use in common syndromes
ICMR · Infectious Diseases · 2019
Ask House about homatropine
Continue into a citation-backed clinical answer with the drug context already attached.
Sources: KD Tripathi 7e, Goodman & Gilman 14e·Verified: 2026-05-10 · House clinical team