Drug reference directory
Drug reference

ibrexafungerp

Triterpenoid (glucan synthase inhibitor)

Triterpenoid (glucan synthase inhibitor)
CDSCO approved
EXCRETION
—
not curated
INTERACTIONS
—
none in our sources
PREGNANCY
X
FDA category + note

Mechanism

An oral antifungal agent belonging to a new class of glucan synthase inhibitors called triterpenoids, with potent activity against Candida species. Maintains antifungal efficacy at low pH.

Indications

Treatment of vulvovaginal candidiasisTreatment of recurrent vulvovaginal candidiasis

Pregnancy & lactation

Pregnancy

X

Lactation

Contraindicated in lactating women.

Related guidelines

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Textbook-sourced·Sources: Harrison 22e·Updated: 2026-05-10